WebIn THP1 cells, treatment with cGAMP decreased the association of STING with calnexin, revealing the departure of STING from the ER (Fig. 2B, ... C. Wang et al., EGFR-mediated tyrosine phosphorylation of STING determines its trafficking route and cellular innate immunity functions. EMBO J. 39, e104106 (2024). WebIncubation of THP-1 NF-κB-eGFP cells for 24 hours with contaminated culture supernatants activates expression of the eGFP reporter which may be easily detected via flow cytometry or light microscopy (1). Presence of amphotericin B in cultures also induces the reporter gene. The THP-1 NF-κB-eGFP cell line is derived from a single-cell clone of ...

Anti-EGFR (C225) ICD (Megf10) CAR THP1 Cell Line

WebTHP1 alone or induced M2-polarized macrophages was used for comparison. (C) EGFR monoantibody Cetuximab suppressed the migration and invasion of Cal27 cells that were … WebDownload scientific diagram EGFR and VEGFR2 are expressed in THP1 and Raji cell lines. A total of 106 cells/well were cultured. (A) VEGFR1 and VEGFR3 were found to be absent in … nyc excelsior plate

Papain Exerts an Anti-atherosclerosis Effect with Suppressed …

Web× Close. The Infona portal uses cookies, i.e. strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc.), or their login data. WebTHP1-def cells are derived from THP-1 human monocytic cells. These are the most commonly used model cell line for the study of inflammasome activation as they express high levels of NLRP3, ASC and pro-caspase-1. THP1-defCASP1 cells are highly deficient for caspase-1 activity (~7 fold reduction). They produce significantly less IL-1β in ... nyc event space