WebApr 9, 2024 · Author summary Idiopathic pulmonary fibrosis (IPF) is a severe chronic lung disease, which is refractory to treatment. The environmental, age-related, and genetic factors increase susceptibility of the lung to injury. Repeated injury and deregulated repair result in scarring of the lung tissue and ultimate loss of respiratory function. … WebJun 14, 2024 · FOXM1 is a transcription factor of the Forkhead family that is required for cell proliferation of normal cells. However, FOXM1 is repeatedly overexpressed in a variety of human cancers, and it has been implicated in all major hallmarks of cancer delineated by Hanahan and Weinberg.
Aberrantly high activation of a FoxM1–STMN1 axis contributes to ...
WebNov 23, 2024 · The transcription factor FOXM1 that regulates multiple proliferation-related genes through selective protein-DNA and protein–protein interactions is now considered an attractive oncotarget. There are several small-molecule inhibitors that indirectly suppress the expression of FOXM1 or block its DNA binding domain (FOXM1-DBD). However, … WebView Mouse Monoclonal anti-FoxM1 Antibody (0.T.181) (NB600-848). Validated Applications: WB, ELISA, Flow, ICC/IF, IHC, IHC-P, IP. Validated Species: Human, … how old is mark spitz the swimmer
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WebMay 28, 2024 · FoxM1 is critical for dividing cells, as it activates expression of genes that facilitate mitotic entry, the mitotic program, and proper cell-cycle progression ( Fu et al., 2008; Korver et al., 1997; Korver et al., 1998; Laoukili et al., 2005; Wang et al., 2005; Wonsey and Follettie, 2005 ). WebMay 5, 2024 · FOXM1 is a transcription factor involved in cellular proliferation and cell cycle progression. Ribeiro et al. show that cyclic expression of a truncated form of a FOXM1 … WebFeb 1, 2024 · It has been found that FoxM1 is frequently dysregulated in multiple cancers, and is emerged as an important molecule implicated in the initiation and progression of cancer. Functionally, it plays... mercury systems 3u