WebFunction. Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G protein-coupled receptors and cause specific … WebOct 1, 2016 · Cofetuzumab pelidotin, also known as PF-06647020 or ABBV-647, is an ADC containing Auristatin-0101 as payload linked, through a cathepsin cleavable linker, to a …
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WebAuristatin F, a synthetic analog of dolastatin 10, is a cytotoxic tubulin modifier with potent and selective antitumor activity. It is an MMAF analog and cytotoxin in Antibody-drug … WebThis invention describes a method of conjugating a cell binding agent such as an antibody with an effector group (e.g., a cytotoxic agent) or a reporter group (e.g., a radionuclide), whereby the reporter or effector group is first reacted with a bifunctional linker and the mixture is then used without purification for the conjugation reaction with the cell binding … cb \u0026 trust
Stable Isotope Products Cambridge Isotope Laboratories
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